Synthesis and Antimicrobial Properties of 1,3,4-Oxadiazole Analogs Containing Dibenzosuberane Moiety

نویسندگان

  • Manjunath Moger
  • Vijay Satam
  • Darshan Raj C. Govindaraju
چکیده

Uma série de dez novos análogos de 1,3,4-oxadiazóis contendo uma parte dibenzosuberano foram sintetizados usando tanto uma aproximação de síntese linear, quanto convergente. Todos os compostos foram caracterizados por espectrometria de massas, espectroscopias no infravermelho (IR), de ressonância magnética nuclear de H (H NMR ) e C (C NMR) e análise elementar. As atividades bactericidas e antifúngicas destes compostos foram avaliadas, determinando-se que entre estes, quatro derivados, especificamente 8a, 8d, 8e e 8j, foram altamente bactericidas e antifúngicos.

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تاریخ انتشار 2013